Neem Giloy

Giloy or Guduchi or Tinospora cordifolia or heart-leaved moonseed is a creeper that is indigenous to India, Bangladesh, Sri Lanka, Nepal, and Pakistan. It grows on trees and is said to have various medicinal benefits. While researchers around the world are looking at the potential benefits of Giloy, the creeper which grows on a Neem tree is said to possess the most medicinal qualities since it also absorbs Neem’s properties.

Neem Giloy and Cancer

According to Ayurveda, Giloy is useful in the treatment of various diseases due to its anti-pyretic, digestive, anti-inflammatory, blood purifying and many other properties. It also helps in building up the body’s immune system. However, very few of these uses are currently backed by scientific evidence. Here are some possible benefits of Neem Giloy in the treatment of cancer:

• In animals, a study revealed that by administering the polysaccharide fraction of Tinospora cordifolia, the metastatic potential of melanoma cells was reduced.
• In another study, it was found that Giloy may prevent some negative side effects of radiation.
• It has anti-neoplastic (anti-tumor) properties.
• Up-regulates anti-tumor activity of tumor-associated macrophages (TAM).
• Displays anti-angiogenesis properties.

Products

• Le’ayur Giloy OR Guduchi (Tinospora cordifolia) Powder 100 Gms – Amazon Link
• Patanjali Divya Giloy Ghanvati – 40Gms (Pack Of 3) 120Gms – Amazon Link
• Himalaya Wellness Pure Herbs Guduchi Immunity Wellness – 60 Tablet – Amazon Link

References & More Information

1. Credit: Beyond Conventional Care Therapies
2. ZenOnco.io Integrative Oncology Cancer Care
3. Manoj Kumar Sarangi, Shasank Soni. A Review on Giloy: The Magic Herb. Inventi Rapid: Planta Activa, 2013(2): 1-4, 2013. Available on Research Gate.
4. P.V. Leyon, G Kuttan. Inhibitory effect of a polysaccharide from Tinospora cordifolia on experimental metastasis. Journal of Ethnopharmacology. Volume 90, Issues 2–3, February 2004, Pages 233-237
5. Priyanka Sharma, Jyoti Parmar, Priyanka Sharma, Preeti Verma, and P. K. Goyal, “Radiation-Induced Testicular Injury and Its Amelioration by Tinospora cordifolia (An Indian Medicinal Plant) Extract,” Evidence-Based Complementary and Alternative Medicine, vol. 2011, Article ID 643847, 9 pages, 2011. 
6. Mahesh Subramanian, Gajanan J. Chintalwar & Subrata Chattopadhyay (2002) Antioxidant properties of a Tinospora cordifolia polysaccharide against iron-mediated lipid damage and γ-ray induced protein damage, Redox Report, 7:3, 137-143, DOI: 10.1179/135100002125000370
7. Jagetia GC, Rao SK (2006) Evaluation of the antineoplastic activity of guduchi (Tinospora cordifolia) in Ehrlich ascites carcinoma bearing mice. Biol Pharm Bull 29(3): 460-466. doi: https://doi.org/10.1248/bpb.29.460. PubMed: 16508146
8. Singh N, Singh SM, Shrivastava P (2005) Effect of Tinospora cordifolia on the antitumor activity of tumor-associated macrophages-derived dendritic cells. Immunopharmacol Immunotoxicol 27(1): 1-14. doi: https://doi.org/10.1081/IPH-51287. PubMed: 15803856.
9. Leyon PV, Kuttan G (2004) Effect of Tinospora cordifolia on the cytokine profile of angiogenesis-induced animals. Int Immunopharmacol 4(13): 1569-1575. doi: https://doi.org/10.1016/j.intimp.2004.06.015. PubMed: 15454110.